An overview of the REFINE ICD trial is shown:



An ICD compared to usual care will increase survival in patients with an EF 0.36 to 0.50, impaired heart rate turbulence (HRT) and abnormal repolarization alternans (TWA) measured at least 2 months after MI.


•    Compare cardiac death rates in ICD vs. control patients.

•    Assess rates of appropriate ICD therapies in ICD patients.

•    Compare arrhythmic syncope rates in ICD vs. control patients.

•    Compare temporal patterns of health-related quality of life in ICD vs. control patients.

•    Evaluate the prognostic significance of DC, in addition to HRT and TWA.

REFINE ICD Clinical Coordinating Centre: TRW Building GE63, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada  |  Phone: 1-855-426-6328  |  Fax: (403) 210-8140  |  Contact Us
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